Multiple Sclerosis: Current and Emerging Disease-Modifying Therapies and Treatment Strategies
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چکیده
منابع مشابه
Multiple sclerosis: current and emerging disease-modifying therapies and treatment strategies.
Multiple sclerosis (MS) is a chronic inflammatory demyelinating central nervous system disease that typically strikes young adults, especially women. The pathobiology of MS includes inflammatory and neurodegenerative mechanisms that affect both white and gray matter. These mechanisms underlie the relapsing, and often eventually progressive, course of MS, which is heterogeneous; confident predic...
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Mia T. Minen, MD Steven Karceski, MD Over the past 18 years, treatments for multiple sclerosis (MS) called disease-modifying therapies (DMTs) have been developed. These therapies are designed to decrease the number of MS attacks, and to slow the progression of the disease. They have become a standard part of the current treatment for MS. There are different classes of the currently available DM...
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Multiple sclerosis (MS) is an autoimmune disease that is characterized by central nervous system inflammation, demyelination, and axon loss. The clinical hallmarks of MS include a pattern of alternating relapses and remissions, and progression of permanent neurologic disability. Several subtypes of MS have been described on the basis of the initial clinical presentation and long-term course of ...
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Classical multiple sclerosis (MS) treatments using first-line injectable drugs, although widely applied, remain a major concern in terms of therapeutic adherence and efficacy. New oral drugs recently approved for MS treatment represent significant advances in therapy. The oral route of administration clearly promotes patient satisfaction and increases therapeutic compliance. However, these drug...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2014
ISSN: 0025-6196
DOI: 10.1016/j.mayocp.2013.11.002